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Diagnostic Support Cows Milk Protein Allergy

Diagnostic Support Cows Milk Protein Allergy

Diagnosing CMPA in infants and young children can be complicated as the symptoms are so broad and non-specific. The key is to spot the symptoms early and have the nutritional solutions readily available to shorten the often long and stressful process of managing the condition.   


After a medical history and physical examination, if there is a suspicion that a child has CMPA, the only valid way to actually confirm CMPA is by performing a food challenge/elimination diet using a therapeutic formula. 

The challenge/elimination diet, which, according to major scientific societies is the gold standard, performed within four weeks is key for the accurate diagnosis of CMPA, and in the long term will avoid prolonged and unnecessary diet restrictions.

Although several different procedures exist to help increase the likelihood of a CMPA diagnosis, such as the serum specific IgE test, skin prick test and patch test, none of these can ultimately prove nor exclude a diagnosis of CMPA. 

Various algorithms exist to diagnose and manage CMPA. The algorithm below refers to the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and is for infants and children with symptoms suggestive of CMPA.

Koletzko S, NiggemannB, Arato A et al. Diagnostic approach and management of cow's-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. JPediatr Gastroenterol Nutr. 2012;55(2):221-9.

For HCP's: Could it be cow's milk protein allergy?

Do you suspect that your patient has a food allergy? 

Cow's Milk Protein Allergy is one of the most common food allergies in the first year of life.

Read more ...

Signs & symptoms: cow's milk protein allergy
The signs and symptoms linked with cow's milk protein allergy, ranging from colic and reflux to constipation, diarrhoea and crying, make diagnosis a real challenge.
Read more ...


Help parents prepare for their visit

In order to raise parents' awareness and prepare them for their visits, Nestle Health Science has developed a cow's milk protein allergy symptoms diary.

Download the symptom diary

Nutritional products for food allergy



Nestlé Health Science has a range of paediatric products that can assist in maximising nutritional intake across a wide range of conditions including food allergies.


ALFARÉ® and ALFAMINO®  are Infant Formula Products for Special Dietary Use. Products are not suitable for general use. ALFAMINO® Junior is a food for special medical purposes specifically formulated for children with severe allergy and/or food intolerances. Products must be used under medical supervision.

Breast milk is best for baby and provides ideal nutrition. Good maternal nutrition is important for preparation and maintenance of breastfeeding. Introducing partial bottle feeding could negatively affect breastfeeding and reversing a decision not to breastfeed is difficult. Professional advice should be followed on infant feeding. Infant formula should be prepared and used exactly as directed or it could pose a health hazard. The preparation requirements and cost of providing infant formula until 12 months of age should be considered before making a decision to formula feed.

Mothers should be encouraged to continue breastfeeding even when their infants have cow’s milk protein allergy. If a decision to use an infant formula for special dietary use is taken, it must be used under medical supervision.