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PKU Sphere 15 20

PKU sphere™

Available in 2 sizes:

  • PKU sphere15 and
  • PKU sphere20

A powdered protein substitute for the dietary management of Phenylketonuria. PKU sphere is Vitaflo’s first glycomacropeptide (GMP) based protein substitute and is suitable from 4 years of age. PKU sphere has a GMP-dominant protein source supplemented with amino acids, bringing patients the potential benefits of GMP without any compromise in nutritional profile. PKU sphere can easily be made to an individual’s preferred volume.


Download the PKU sphere datacard

PKU sphere is a food for special medical purposes and must be used under medical supervision.

What's GMP?
Glycomacropeptide (GMP) is a protein naturally low in phenylalanine. Protein substitutes based on GMP are regularly perceived to be more palatable than those based on amino acids1,2. Palatability of protein substitutes is key to compliance,3 making GMP an ideal alternative protein source for Phenylketonuria (PKU).
  1. Van Calcar, SC. et al. Improved nutritional management of phenylketonuria by using a diet containing glycomacropeptide compared with amino acids.
  2. Daly, A. et al. SSIEM abstract 2016: Impact of the amino acid profile of casein glycomacropeptide on metabolic control in children in PKU. 2016 Am J Clin Nutr. 2009; 89 (4): 1068 – 77
  3. Giovannini, M., et al. Phenylketonuria: nutritional advances and challenges. Nutr Metab (London) 2012
Key Features:
  • Available in 15g and 20g PE pre-measured sachets.
  • Contains a full range of micronutrients and DHA.
  • Each 15g PE sachet contains 28mg Phe and Each 20g PE sachet contains 36mg Phe.
  • Available in either Red berry or Vanilla flavour.
  • Lowest calorie GMP product available, only 91 calories and 1.5g sugar per 15g PE sachet and only 120 calories and 2.2g sugar per 20g PE sachet.
PKU sphere is for use in the dietary management of Phenylketonuria (PKU)
Prescribing Information
PKU sphere15: 27g x 30 x 4 with 5 repeats

PKU sphere20: 35g x 30 x 4 with 5 repeats
PBS Prescribing Information

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Our product range for PKU

Inborn Errors of Metabolism