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TYR sphere™

TYR sphere™

A powdered protein substitute for the dietary management of Tyrosinaemia. TYR sphere20 is Vitaflo’s first glycomacropeptide (GMP) based protein substitute for Tyrosinaemia and is suitable from 4 years of age. TYR sphere20 has a GMP-dominant protein source supplemented with amino acids, bringing patients the potential benefits of GMP without any compromise in nutritional profile.

One sachet TYRsphere20 contains 20g Protein Equivalent (PE).

Available in Red Berry

Download the TYRsphere20 datacard


TYR sphere20 is a food for special medical purposes and must be used under medical supervision.

What is GMP?
Glycomacropeptide (GMP) is a protein naturally low in phenylalanine and tyrosine. Protein substitutes based on GMP are regularly perceived to be more palatable than those based on amino acids1,2. Palatability of protein substitutes is key to dietary compliance3, and so this, combined with its’ low tyrosine content means GMP is an ideal alternative protein source for Tyrosinaemia.

1. Van Calcar, SC. et al. Improved nutritional management of phenylketonuria by using a diet containing glycomacropeptide compared with amino acids.

2. Daly, A. et al. SSIEM abstract 2016: Impact of the amino acid profile of casein glycomacropeptide on metabolic control in children in PKU. 2016 Am J Clin Nutr. 2009; 89 (4): 1068 – 77

3. Giovannini, M., et al. Phenylketonuria: nutritional advances and challenges. Nutr Metab (London) 2012

Key Features
  • Available in 20g PE pre-measured sachets.
  • Contains a full range of micronutrients including DHA.
  • Each 20g PE sachet contains <11mg tyrosine and 36mg phenylalanine.
  • Available in Red berry.
  • Low calorie (120kcal/sachet), Low sugar (1.4g sugar/sachet) and a source of DHA (110mg/sachet).
TYR sphere20 is for use in the dietary management of Tyrosinaemia (TYR).
Prescribing information
TYR sphere20: 35g x 30 x 4 with 5 repeats.
HCP TYR sphere20 brochure

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Inborn Errors of Metabolism