Glycomacropeptide (GMP) is a protein naturally low in phenylalanine and tyrosine. Protein substitutes based on GMP are regularly perceived to be more palatable than those based on amino acids1,2. Palatability of protein substitutes is key to dietary compliance3, and so this, combined with its’ low tyrosine content means GMP is an ideal alternative protein source for Tyrosinaemia.
1. Van Calcar, SC. et al. Improved nutritional management of phenylketonuria by using a diet containing glycomacropeptide compared with amino acids.
2. Daly, A. et al. SSIEM abstract 2016: Impact of the amino acid profile of casein glycomacropeptide on metabolic control in children in PKU. 2016 Am J Clin Nutr. 2009; 89 (4): 1068 – 77
3. Giovannini, M., et al. Phenylketonuria: nutritional advances and challenges. Nutr Metab (London) 2012